The system runs through the whole aseptic filling process, and through-wall cross-level transport system is a common tool. Many steps such as cleaning and sterilization are involved in a traditional way, but one-time cross-level wall-crossing system can solve this problem more safely and conveniently. The system provides a simple, safe and reliable scheme for transfer and transportation of a large number of fluids in different function rooms. The whole system realizes aseptic transmission of multi-pipeline fluid through a stainless steel channel and pre-sterilized disposable components, and meets a variety of process requirements: 1, the same level through wall 2, cross-level through wall 3, high activity and low activity transport (ADC, etc.) 4, toxic and non-toxic transmission (virus vaccine, etc.).
Figure 4: Aseptic Transmission System
How to quickly transfer items (liquid, aluminum-plastic covers, rubber plugs and tools, etc.) to or from the controlled environment in isolator, RTP(Rapid Transfer Port) is an ideal choice. RTP system consists of two parts: α port and β port. α port is installed on isolator door and is normally closed, while β port components include a flange, a seal and a door, which can be divided into three types: stainless steel transfer barrel, plastic transfer barrel and disposable transfer bag. After β port components is connected with α port, the operator opens RTP door from inside of isolator by gloves, and then transfers pre-sterilized material to inside of isolator, and the whole process ensures isolation from outside.
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